来自生物质的,针对特定的和生态更安全的杀虫剂活性成分
Tejas Goculdas1,2, Maximus Ramirez2, Michael Crossley3
1Catalysis Center for Energy Innovation, University of Delaware, 221 Academy St., Newark, 19716, DE, USA.
ChemSusChem
|June 26, 2024
概括
新的生物质衍生碳酸可提供可持续的害虫防治. 这些环保的杀虫剂的效果与传统的选择相比,具有较低的毒性和较低的生产成本.
科学领域:
- 农业化学 农业化学
- 有机合成 有机合成
- 可持续化学 可持续化学
背景情况:
- 传统的杀虫剂对环境构成风险,需要可持续的替代品.
- 来自生物质的化合物为开发环保作物保护剂提供了可再生来源.
- 素和素是从生物质中衍生出来的关键平台化学物质.
研究的目的:
- 从生物质衍生的单体合成基于胺基的新型杀虫剂活性成分.
- 评估这些新化合物的杀虫活性和生态毒性.
- 评估开发的生物基杀虫剂的经济可行性.
主要方法:
- 通过还原性氨基化合成,然后通过furfural和 vaniillin的碳化.
- 在合成中使用了可回收的催化剂 (Rh/Al2O3和La(OTf) 3).
- 杀虫剂活性是通过LC50值来确定的,并且对非目标物种预测生态毒性.
主要成果:
- 一种基于furfural的碳酸盐杀虫剂被合成,产量为88%.
- 生物基碳酸盐的杀虫性能与卡博相提并论 (LC50:254.22与251.25μg/cm2相比).
- 预计非目标水生和陆生生物的生态毒性明显较低.
结论:
- 来自生物质的碳酸盐是传统农药的可行和可持续的替代品.
- 合成策略可以适应其他生物基化物,从而创造出各种各样的潜在杀虫剂.
- 技术经济分析表明有竞争力的销售价格,强调经济可行性.
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