空气中纳米粒子度与加拿大两个最大城市的死亡风险增加有关
Marshall Lloyd1, Toyib Olaniyan2, Arman Ganji3
1Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Québec, Canada.
概括
长期暴露于室外超细颗粒,不受管制的空气污染物,与死亡风险增加有关,特别是呼吸道原因. 这凸显了需要采取监管行动来保护公众健康免受这些常见的环境危害.
科学领域:
- 环境健康科学 环境健康科学
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 户外细颗粒物 (PM2.5) 在全球造成数百万人的死亡.
- 超细颗粒 (UFPs,<100 nm) 对健康的长期影响尚不太清楚.
- 在城市地区,UFP很普遍,目前不受监管.
研究的目的:
- 估计长期暴露于户外UFP和死亡率之间的关联.
- 调查与UFP暴露相关的特定原因死亡风险.
- 量化加拿大城市的UFPs所造成的死亡负担.
主要方法:
- 从2001年至2016年利用了大量基于人口的队列.
- 将住宅地址与室外空气污染数据联系起来.
- 采用Cox的比例危险模型来评估死亡风险.
主要成果:
- 增加的UFP暴露与更高的非意外死亡率相关 (HR=1.073).
- 与呼吸道死亡率 (HR=1.174) 发现的最强相关性.
- 据估计,在蒙特利尔和多伦多,每年约有1100人因UFP死亡.
结论:
- 户外的UFP与死亡率的增加有关,这强调了严重的公共卫生风险.
- 针对UFP的监管干预措施的潜力,以改善人口健康.
- 观察到的粒子大小的混表明,之前的研究可能低估了UFP风险.
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