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Updated: Jun 17, 2026

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结构-活性研究 替代,核心扩展和二甲二胺G-四重复合联体的结构-活性研究 导致强大的抗松体剂

Alessandra Benassi1, Pablo Peñalver2, Manuel Pérez-Soto2

  • 1Department of Chemistry, University of Pavia, 27100 Pavia, Italy.

Journal of medicinal chemistry
|June 26, 2024
PubMed
概括

针对G-四复合体的新型纳夫他林二胺 (NDI) 配体显示出强大的抗寄生虫活性. 化合物16显示出对Trypanosoma brucei和Leishmania major的高选择性和有效性.

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