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抗药结核病例发现策略:范围审查

Susanna S van Wyk¹, Marriott Nliwasa², Fang-Wen Lu³

¹Centre for Evidence Based Health Care, Division of Epidemiology and Biostatistics, Department of Global Health Stellenbosch University, Cape Town, South Africa.

JMIR public health and surveillance

|June 26, 2024

概括

鉴定耐药结核病 (DR-TB) 病例至关重要. 这次审查发现DR-TB病例发现策略的有效性证据有限,强调需要更多的研究和标准化报告.

科学领域:

公共卫生公共卫生
传染性疾病传染性疾病
流行病学流行病学

背景情况:

针对耐药结核病 (DR-TB) 进行有效的病例发现对于疫情控制和患者的治疗结果至关重要.
缺乏对DR-TB病例发现策略的有效性,成本效益,可接受性和可行性的系统审查.
对于DR-TB病例检测的初级研究范围在很大程度上是未知的.

研究的目的:

系统地评估有关DR-TB病例发现策略的现有文献.
确定和评估改善DR-TB病例检测的研究.
为有关DR-TB病例调查的研究,政策和实践提供信息.

主要方法:

在多个学术数据库中进行搜索 (MEDLINE,Embase,Cochrane图书馆等). 没有日期或语言限制.
包括系统审查,试验,定性研究和诊断测试准确性研究,重点关注DR-TB病例检测.
排除了现有结核病症状或诊断的患者的研究,以及基于实验室的研究.

主要成果:

选了3646个标题/摘要和236个全文文章,确定了6个系统评论和61个初级研究.
审查的重点是接触调查 (家庭,航空公司) 和普遍与选择性药物耐药性测试.
主要研究包括接触/爆发调查,流行病学分析和计划描述;没有确定任何试验.

结论:

关于DR-TB病例发现策略的有效性,成本效益,可接受性和可行性存在重大知识差距.
现有的描述性评论可以更新,但初级研究有限.
迫切需要对DR-TB病例调查研究中的术语,设计和报告进行标准化.

关键词:

结核病的症状结核病的症状抗结核药物是一种抗结核药物.诊断诊断诊断诊断诊断诊断药物耐药性耐药性药物耐药性耐药性耐药性耐药性耐药性耐药结核病的治疗方法药物耐药结核病病例检测检测情况药物耐药结核病病例的发现耐药结核病接触调查接触调查对耐药结核病进行查.药物治疗药物治疗具有多种耐药性的药物.范围审查范围审查审查查检查查检查查检查查检查策略策略策略策略系统性审查系统性审查结核病是一种肺结核病.

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