在脑患者的一生中感觉症状
Ariel M Lyons-Warren1, Danielle Guez-Barber2, Sruthi P Thomas3
1Section of Pediatric Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
在脑 (CP) 中,感觉症状很常见,随着年龄的增长而减弱,特别是触觉过敏. 这种下降在运动障碍较大的个体中更为明显,这表明与年龄相关的感官处理变化.
科学领域:
- 神经科学是一个神经科学.
- 发育儿科 发育儿科
- 康复医学 康复医学 康复医学
背景情况:
- 在患有脑 (CP) 的个体中,感官症状很普遍.
- 了解这些症状的寿命流行率对于综合护理至关重要.
- 这项研究调查了CP人口中不同年龄组的感官处理变化.
研究的目的:
- 为了估计脑 (CP) 患者在整个生命周期中感官症状的患病率.
- 检查CP中年龄,功能状态和感官症状之间的关系.
- 为了确定特定的感官处理模式,随着年龄的增长而改变CP的个体.
主要方法:
- 一项采用自我报告的感官处理量表 (SPS-I) 的横截面研究.
- 数据通过研究电子数据捕获 (REDCap) 从MyCP社区注册表中的CP患者或他们的护理人员收集的数据.
- 统计分析包括年龄关联的皮尔森相关性和功能状态比较的ANOVA.
主要成果:
- 97%的参与者报告至少有一个令人烦的感官症状.
- 总体感官症状和低敏感性,特别是触觉性,随着年龄的增长而下降 (p < 0.0001).
- 感觉症状随着功能障碍的增加而增加 (p < 0.0001),与年龄相关的低敏感性下降在严重运动障碍患者中最为显著.
结论:
- 过敏性,特别是触觉性,随着年龄的增长而在CP患者中减弱.
- 与年龄相关的过敏性降低可能与功能状态有关.
- 建议进行进一步的研究,以探索降低过敏度与CP的其他与年龄相关的变化 (如疼痛增加) 之间的联系.
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