双极性障碍过程中的心理能力理论:使用混合模型的纵向研究
Katharina Stix1, Nina Dalkner1, Susanne A Bengesser1
1Department of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Auenbruggerplatz 31, 8036 Graz, Austria.
Psychiatry research
|June 26, 2024
概括
患有双相情感障碍的个体在思维理论 (ToM) 中始终表现出缺陷,即理解他人的心理状态的能力. 这些 ToM 困难随着时间的推移而保持稳定,这表明它们可能是该疾病的内表型特征.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 心理理论 (ToM) 缺陷在双相情感障碍中经常被观察到.
- 在双相情感障碍中,ToM的纵向变化和稳定性仍未得到充分研究.
- 了解ToM稳定性对于评估疾病进展和治疗至关重要.
研究的目的:
- 为了纵向比较双相情感障碍和健康对照的euthymic个体的思维理论 (ToM) 能力.
- 在四年半的时间内调查ToM的稳定性.
- 为了确定 ToM 缺陷和双相情感障碍之间的关系.
主要方法:
- 纵向研究设计比较euthymic双极个体 (n=91) 和健康对照 (n=91).
- 使用眼睛测试 (RMET) 阅读心智的ToM评估.
- 使用线性混合模型进行统计分析,以比较随时间推移的群体表现.
主要成果:
- 与健康对照组相比,双极患者在RMET上得分始终较低.
- 通过RMET得分测量的ToM能力在四年半的研究期间在双相情感患者中保持稳定.
- 在随访期间,在两组中都没有观察到RMET得分的显著变化.
结论:
- 心理理论 (Theory of Mind, ToM) 缺陷似乎是双相情感障碍患者中一种稳定的特征.
- 这些稳定的ToM缺陷可能代表着双极性障碍的潜在内分类型.
- 这些发现可以为改善对双相情感障碍的识别,评估和有针对性的干预提供信息.
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