最近出现精神分裂症患者的失败主义的表现信念:与认知和负面症状的关系
Tess F Filip1, Gerhard S Hellemann2, Joseph Ventura3
1Department of Psychological and Brain Sciences, The University of Iowa, Iowa City, IA, United States of America.
Schizophrenia research
|June 26, 2024
概括
失败主义的表现信念在最近出现的精神分裂症中升高,并调解神经认知缺陷和负面症状之间的联系. 这些发现支持在精神分裂症治疗的早期针对这些信念.
科学领域:
- 精神病学是一个精神病学.
- 认知神经科学 认知神经科学
背景情况:
- 精神分裂症的负面症状与认知缺陷和日常功能有关.
- 假设失败主义的绩效信念 (DPB) 可以调解这种关系.
- 人们对最近出现的精神分裂症 (ROSz) 中的DPB知之甚少.
研究的目的:
- 测试DPB,神经认知,负症状和ROSz中的功能之间的关联.
- 检查DPB是否调解了ROSz.中神经认知和负面症状之间的联系.
主要方法:
- 52名参与者 (32名ROSz,20名健康对照者) 完成了神经认知,DPB,负症状和功能评估.
- 皮尔森相关性检查了双变量关系.
- 引导回归通过DPB测试了间接效应.
主要成果:
- DPB在ROSz中升高,并与神经认知,负面症状和功能相关.
- 通过DPB发现神经认知对负面症状有显著的间接影响,证实DPB是部分调解者.
结论:
- 这些发现支持ROSz.中负面症状的认知模型.
- DPB在早期精神分裂症中升高,并将认知缺陷与临床结果联系起来.
- DPB代表了精神分裂症早期治疗的潜在目标.
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