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患有MRI阴性的患者的失眠:相关因素和3D-pCASL脑血流 perfusion 变化

Bofei Tan¹, Xianrui Xu², Qiang Liu³

¹Clinical Medical College, Ningxia Medical University,Yinchuan 750004, Ningxia Province, China.

Epilepsy & behavior : E&B

|June 26, 2024

概括

失眠影响了19.2%的MRI阴性患者. 夜间发作,焦虑和白天过度的嗜睡是关键因素,左下杏仁体脑血流可能表明潜在的潜在机制.

科学领域:

神经学神经学
睡眠医学睡眠医学
神经成像是一种神经成像.

背景情况:

失眠是中常见的并发症.
了解MRI阴性中失眠的具体因素和机制对于有针对性的干预至关重要.

研究的目的:

在MRI阴性患者中识别与失眠相关的因素.
通过神经成像来探索这种人群中失眠的潜在病理机制.

主要方法:

对73名MRI阴性患者的回顾性研究.
使用了失眠严重程度指数 (ISI),爱普沃思睡眠度量表 (ESS) 和焦虑/抑郁度量表.
进行了3D伪连续动脉旋转标记 (3D-pCASL),以测量特定大脑区域的脑血流 (CBF).

主要成果:

19.2%的患者经历了失眠.
夜间发作,焦虑和过度白天嗜睡 (EDS) 独立地与失眠有关.
在失眠患者的左桃体中观察到显著较低的CBF.

结论:

失眠在MRI阴性中很普遍,与夜间发作,焦虑和EDS有关.
减少左桃体CBF可能是相关失眠的关键病理机制.

关键词:

3D-pCASL 3D-pCASL 在线播放失眠是一种失眠.左侧的杏仁体是左侧的磁力共振成像阴性.夜间发作在夜间发作.

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