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Updated: Jun 23, 2025

Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease
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通过肠道微生物群调节mercaptopurine的肠道毒性和药理动力学

Jiamin Xu1, Jiaqi Han2, Siyao Jin2

  • 1Department of Pharmacy, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China; Department of Pharmacy, Peking University Third Hospital, Beijing 100191, China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|June 26, 2024
PubMed
概括

默卡普托普林 (6-MP) 破坏肠道微生物群,恶化肠道损伤和白血病治疗中的毒性. 肠道微生物影响6-MP代谢和S-adenosylmethionine (SAM) 水平,这对药物的疗效和安全至关重要.

关键词:
我们的肠道微生物群.肠道损伤 肠道损伤 肠道损伤梅卡普托氨酸是什么?药理动力学 药理动力学这是一种S-adenosylmethionine.

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