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Updated: Jun 23, 2025

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由CTLA-4和PD-1阻断诱导的irAE结肠炎通过TNF阻断和肠道微生物调节得到改善

Ruiwei Ye1, Hao Zheng2, Dandan Yang2

  • 1Shanghai Baoshan Luodian Hospital, School of Medicine, Shanghai University, Shanghai 201908, China; Shanghai Marine Medical Engineering Integration Innovation Center，School of Medicine, Shanghai University, Shanghai 200444, China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|June 26, 2024
PubMed
概括

与免疫检查点疗法 (DICB) 一起使用Infliximab阻止TNF-α可减轻结肠炎. 这种方法恢复了肠道微生物群的平衡,揭示了DICB,TNF-α和肠道细菌参与免疫相关不良事件的反循环.

关键词:
DICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICBDICDICBDICDICDICDICD这就是Infliximab.伊雷性结肠炎是什么?微生物组和代谢学

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