酸盐在子子组织中的毒动力学和子衍生的潜在生物可访问性评估
Shizhong Yue1, Ruiping Wang1, Caide Huang2
1Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, PR China; International Joint Laboratory of Agricultural Food Science and Technology of Universities of Shandong, Dezhou University, Dezhou 253023, PR China.
Ecotoxicology and environmental safety
|June 26, 2024
概括
土壤中的 (Se) 污染影响地,积累量因组织和度而异. 来自地的Se具有很高的生物可访问性,对捕食者构成风险.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 生态毒理学 生态毒理学
背景情况:
- 人类活动导致 (Se) 污染,引发生物安全问题.
- 在陆地食物链中至关重要,使它们的Se吸收显著.
- 了解虫中的Se毒动力学对于评估生态风险至关重要.
研究的目的:
- 为了研究酸盐 (Se(VI)) 在Eisenia fetida中的毒动性 (TK) 过程.
- 评估土中积累的Se的生物可访问性和食用风险.
- 为了解土壤的生物足迹和生态危害提供数据.
主要方法:
- 一个分区的毒动力学 (TK) 建模被用来研究Se的吸收,分布和消除在虫中.
- 在体外模拟的胃肠道消化过程中,评估了来自组织的Se的生物可访问性.
- 在前阴茎 (PC),后阴茎 (PoC) 和总组织 (TT) 中的Se度随着时间的推移和不同剂量的分析.
主要成果:
- 在土PC和TT中以时间和剂量依赖的方式积累Se.
- TK模型准确地预测了PC和TT中的Se动力学,但不是PoC.
- 在低度下,地TT显示出更快的Se吸收和消除,对家禽具有更高的生物可访问性 (66.2584.35%).
结论:
- 虫中的毒性动力学是组织特异的,并且依赖于度.
- 地中的高Se生物可访问性对捕食者构成潜在的食物营养风险.
- 这项研究提供了评估土壤Se影响和生态危害的基础数据.
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