在减少射出分数的患者中进行大动脉置换手术. 患病率和随访情况
Santiago Decotto1, Gonzalo Fernandez Villar1, Maria Eugenia Knorre1
1Cardiology Department, Hospital Italiano de Buenos Aires, Argentina.
Current problems in cardiology
|June 26, 2024
概括
大约10%的严重大动脉狭窄 (AS) 患者接受大动脉置换手术 (SAVR),左心室喷射率 (LVEF) 降低. 其中一半的患者在SAVR后出现了改善的LVEF.
科学领域:
- 心血管外科心血管外科
- 心脏生理学 心脏生理学
背景情况:
- 有限的数据存在于手术大动脉置换 (SAVR) 对于大动脉狭窄 (AS) 在减少左心室喷射率 (LVEF <55%) 的患者.
- 了解这种患者群体的患病率和结果对于临床决策至关重要.
研究的目的:
- 为了确定SAVR在AS患者的患病率,LVEF<55%.
- 评估该队列中SAVR后6个月随访后LVEF的改善情况.
主要方法:
- 对接受SAVR治疗AS的患者进行回顾性分析,LVEF<55%.
- 定义"改进的LVEF"为6个月后比基线增加10%.
- 收集了手术前LVEF,住院死亡率和随访时LVEF的数据.
主要成果:
- 在685名患者中,11.4% (n=78) 患有SAVR,LVEF<55%.
- 手术前 LVEF 的中位数为 45%. 住院死亡率为5.1%.
- 在6个月后,69名评估患者中有50.7% (n=35) 显示LVEF有所改善.
结论:
- 在接受SAVR的重症AS患者中,约有10%的患者出现LVEF降低.
- 在这些患者中,很大一部分 (一半) 在SAVR后经历了LVEF改善.
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