嗅觉功能障碍和慢性病:一个全面的审查
Sara Morales Palomares1, Mauro Parozzi2, Gaetano Ferrara3
1Italian Nephrological Nursing Society (SIAN), Olbia, Italy; Department of Pharmacy, Health and Nutritional Sciences (DFSSN), University of Calabria, Rende, Italy; Department of Nephrology, Dialysis and Transplantation, Annunziata Hospital, Cosenza, Italy.
概括
嗅觉功能障碍,包括厌氧症,影响超过一半的慢性病 (CKD) 患者. 移植可能会恢复气味,但需要进一步的研究才能获得更好的治疗方法.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 生活质量研究 生命质量研究
背景情况:
- 慢性病 (CKD) 是一个主要的全球健康问题.
- 嗅觉功能障碍显著影响CKD患者的生活质量.
- 了解CKD中嗅觉障碍对于患者护理至关重要.
研究的目的:
- 系统地审查慢性病患者的患病率,影响和治疗方法.
- 在慢性病的背景下,综合有关嗅觉功能障碍的当前知识.
- 确定研究缺口和未来的方向来管理CKD的嗅觉障碍.
主要方法:
- 根据阿克西和奥马利框架和PRISMA-S指导方针进行范围审查.
- 在PubMed/Medline,Embase,CINAHL和Cochrane图书馆进行的搜索.
- 纳入标准侧重于有嗅觉功能障碍的CKD患者;分析了17项涉及4025名患者的研究.
主要成果:
- 超过55%的CKD患者经历了嗅觉变化,其中8.5%患有厌氧症.
- 导致气味丧失的因素包括尿素毒素,透析,电解质失衡和营养不良.
- 观察到移植后嗅觉功能的潜在恢复.
结论:
- 嗅觉功能障碍在CKD患者中很普遍,受疾病特异性因素的影响.
- 腎臟移植對嗅覺功能恢復有希望.
- 需要标准化研究方法和纵向研究来改善理解和管理.
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