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Updated: Jun 22, 2025

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
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与疾病相关的GαS变体内的相互作用网络,其特点是综合性生物物理方法

Kara Anazia1, Lucien Koenekoop2, Guillaume Ferré1

  • 1Department of Chemistry, University of Florida, Gainesville, Florida, USA.

The Journal of biological chemistry
|June 26, 2024
PubMed
概括

GαS蛋白子单元的突变破坏了细胞信号传递,导致疾病. 这项研究使用光谱学和计算来揭示这些GαS突变背后的结构机制,从而对它们的功能影响进行了精细的分类.

关键词:
这是一种G蛋白质蛋白质,G蛋白质蛋白质.G蛋白结合受体 (GPCR) 是一种这是一个GTPase.癌症 癌症 癌症 癌症 癌症分子动力学 (MD) 是指分子动力学.核磁共振 (NMR) 是一种核磁共振技术.

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