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通过检测基于超声波向量流成像的壁剪应力来预测易受伤害的动脉斑块

Xiang Zhang¹, Huanhuan Ding¹, Xiaoli Ji¹

¹Department of Ultrasonography, The Third Affiliated Hospital of Shanghai University, Wenzhou People's Hospital, Wenzhou Third Clinical Institute Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang, China.

Journal of vascular surgery

|June 26, 2024

概括

超声波矢量流成像 (V-流) 测量了带斑块壁切削应力 (WSS). 最大WSS (WSS max) 显示了评估斑块内新血管化 (IPN) 和预测斑块脆弱性的潜力.

科学领域:

心血管成像和诊断服务
生物医学工程生物医学工程
血管生物学血管生物学

背景情况:

Carotid 斑块的脆弱性是心脑血管事件的关键风险因素.
内斑内新血管化 (IPN) 是心动脉斑脆弱性的关键指标.
准确评估IPN对于风险分层至关重要.

研究的目的:

评估超声波矢量流成像 (V-流) 在测量状板壁剪切应力 (WSS) 中的实用性.
为了确定V流衍生WSS参数与IPN的范围之间的相关性.
评估WSS在预测斑块脆弱性的潜力.

主要方法:

140名患者被分为斑块,狭窄和对照组.
使用V-流量测量三个特定斑块位置的平均WSS (WSS平均值) 和最大WSS (WSS最大值).
76名患者进行了对比增强超声波,以量化IPN及其与WSS的关系.

主要成果:

与最大厚度的对照组和斑块组相比,狭窄组的WSS max显著更高.
与上游和下游部分的对照组相比,狭窄组的WSS平均值较低.
带有IPN增强的板块显示出明显更高的WSS值,最厚部分的WSSmax与IPN等级正相关 (r=0.508).
在评估IPN时,WSSmax表现出比WSS平均值更高的疗效,AUC为0.7762.

结论:

V-流是一种有效的工具来测量WSS在动脉斑块.
WSS max是评估IPN的一个有前途的指标,并有可能预测喉斑块的脆弱性.

关键词:

动脉样硬化的斑块.与对比度增强的超声波.内部斑块新血管化的过程.超声波超声波是指超声波的使用.墙壁剪切应力压力是什么

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