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Updated: Jun 22, 2025

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暴露于煤尘会通过激活IL6/ERK1/2/SP1信号通路而加剧认知障碍

Fulin Cai1, Sheng Xue2, Zan Zhou3

  • 1The First Affiliated Hospital, Anhui University of Science and Technology, Huainan, Anhui, China; Anhui University of Science and Technology, Huainan 232001, China.

The Science of the total environment
|June 26, 2024
PubMed
概括

煤尘暴露会使阿尔茨海默氏症和MCI患者的认知障碍恶化. 它通过提高INTERLEUQIN-6 (IL6) 和APOLIPROTEIN E4 (AOPE4) 水平增加神经炎症,从而损害神经元.

关键词:
阿尔茨海默氏症 (AD) 是一种疾病.在阿波利波蛋白E4 (APOE4) 中.煤灰 (CD) 是一种煤灰.炎症因子是一种炎症因子.互白素-6 (IL6) 是一种蛋白质.

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