在波多黎各年轻人的纵向研究中,持久的猫主和喘
Pooja E Mishra1, Yueh-Ying Han1, Kyla Hill2
1Division of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
概括
从小到学龄,持久养猫与波多黎各年轻人中喘几率显著降低有关. 养狗与喘或过敏敏感性没有显著关联.
科学领域:
- 环境健康 环境健康
- 儿科过敏 儿科过敏
- 流行病学 流行病学
背景情况:
- 关于物暴露和儿童喘存在相互矛盾的发现.
- 没有先前的研究检查了从幼年到学龄的持续物暴露.
- 波多黎各的年轻人经历了不成比例的高喘率.
研究的目的:
- 调查儿童时期持续拥有猫或狗与喘发育之间的关联.
- 评估持续物所有权与波多黎各年轻人的过敏敏感性之间的联系.
主要方法:
- 对384名波多黎各年轻人的前性队列研究.
- 定义持久的物所有权是从生命早期 (怀孕/第一年) 到学龄的持续所有权.
- 使用后勤回归来分析喘和过敏敏感性 (IgE ≥0.35 IU/mL).
主要成果:
- 持久养猫与68%降低了喘的几率有关,在对共变量进行调整后.
- 持久拥有猫与一般过敏敏感性或猫过敏原特定敏感性无关.
- 持久养狗没有与喘或过敏敏感性有显著的关联.
结论:
- 从幼年到学龄阶段持续拥有一只猫,表明波多黎各年轻人与喘有相反的关联.
- 研究结果表明,早期,持续的猫暴露对这种人群中喘发病的潜在保护作用.
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