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Updated: Jun 22, 2025

Stereotaxic Injection of a Viral Vector for Conditional Gene Manipulation in the Mouse Spinal Cord
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Stereotaxic Injection of a Viral Vector for Conditional Gene Manipulation in the Mouse Spinal Cord

Published on: March 18, 2013

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对Fcrls的转基因向创建了一个高效的构成性活跃的微质Cre线,具有差异化的特异性

Tobias Kaiser1,2, Jordan Dattero3,4, Liang Li3,2

  • 1McGovern Institute for Brain Research at MIT, Cambridge, Massachusetts 02139 tkaiser@mit.edu fengg@mit.edu.

eNeuro
|June 26, 2024
PubMed
概括

研究人员开发了一种新的工具,Fcrls-2A-Cre小鼠,用于精确地基因修改小质细胞,大脑的免疫细胞. 这为研究大脑健康和疾病提供了高效和特定的操纵.

关键词:
这就是BAM BAM BAM.创意的创意,就是创造的.创建2ERT2 的时间.在 Fcrls-Cre 中使用.微质细胞中的微质细胞这是神经免疫系统.

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In Vivo Direct Reprogramming of Resident Glial Cells into Interneurons by Intracerebral Injection of Viral Vectors12:26

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相关概念视频

Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
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