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Updated: Jun 22, 2025

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
18:10

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Published on: June 16, 2011

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尽管存在遗传约束,STAT2对 NS5 病毒的耐药性的演变却发生了多次

Ethan C Veit1, Madihah S Salim1, Mariel J Jung1

  • 1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature communications
|June 26, 2024
PubMed
概括

寨卡病毒和登革热病毒对抗STAT2,一个关键的免疫调节器,导致疾病. 进化表明,对这种对抗性的抵抗在哺乳动物中出现了多次,但往往是以健康成本.

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