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ASAH1通过DUSP5抑制驱动的MAP激酶通路的激活来促进TNBC,并代表了治疗的脆弱性

Kiran Kumar Reddi1, Suresh Chava1, Siva Chander Chabattula1

  • 1Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL, USA.

Cell death & disease
|June 26, 2024
PubMed
概括

N-乙辛氨基胺基酶1 (ASAH1) 驱动三阴性乳腺癌 (TNBC) 的生长. 抑制ASAH1和MAPK通路为TNBC提供了潜在的新疗法.

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