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Updated: Jun 22, 2025

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通过METTL3介导的染色质接触,通过衰老过程中的代谢重编程促进应力颗粒相分离

Chen Wang1, Hideki Tanizawa2,3, Connor Hill4

  • 1Department of Experimental Therapeutics, University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA.

Nature communications
|June 26, 2024
PubMed
概括

甲基转移酶复合体 (METTL3) 协调基因表达和染色质结构,以控制细胞衰老. 这涉及代谢重编程和相分离,影响细胞周期mRNA转化.

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