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Updated: Jun 26, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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[整个外体序列检测揭示了初级中枢神经系统淋巴瘤的基因突变特征]

Qi-Qi Jin1, Hao-Yun Jiang1, Ye Han2

  • 1Department of Hematology, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China.

Zhongguo shi yan xue ye xue za zhi
|June 27, 2024
PubMed
概括

原发性中枢神经系统淋巴瘤 (PCNSL) 的整体外基因组测序揭示了18名患者经常发生的体质误解突变,主要是C>T. 关键驱动基因涉及RTK-RAS,Wnt,NOTCH和Hippo途径在PCNSL病变发生过程中.

关键词:
主要的中枢神经系统淋巴瘤;整个外体序列;体质突变;瘤突变负担.

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