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Updated: Jun 22, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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基于混合咖啡酸的DHFR抑制剂作为新型抗微生物和抗癌剂

Renu Sehrawat1, Ritu Pasrija2, Priyanka Rathee3

  • 1Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, India.

Antibiotics (Basel, Switzerland)
|June 27, 2024
PubMed
概括

咖啡酸的新型1,2,4-三类型显示出强大的抗癌和抗菌活性. 化合物CTh7抑制二叶酸减少酶 (DHFR) 并表现出细胞毒性,而CTh3和CTh4则表现出显著的抗菌作用.

关键词:
这是一种DHFR抑制剂.这是一种抗癌药物.抗微生物药物是一种抗菌药物.咖啡酸是一种咖啡酸.在形设计中.

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