导航十字路口:在炎症性肠道疾病中,sarcopenia和sarcopenic肥胖症
Valentin Calvez1, Guia Becherucci1, Carlo Covello1
1CEMAD Digestive Disease Center, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Catholic University of Rome, 00168 Rome, Italy.
Biomedicines
|June 27, 2024
概括
肉,肌肉质量和力量的损失,在炎症性肠道疾病 (IBD) 中很常见. 管理包括运动,营养和针对肠-肌肉轴的疗法,以改善患者的治疗结果.
科学领域:
- 胃肠道学和肌肉骨健康
背景情况:
- 炎症性肠病 (IBD) 是一种全身性疾病,具有显著的胃肠道和肠外表现.
- 标志着肌肉质量和力量减少的萨尔科佩尼亚在克罗恩病 (52%) 和性结肠炎 (37%) 中非常普遍.
研究的目的:
- 提供IBD中肉症的全面审查,涵盖诊断方法,病理生理学,临床影响和管理策略.
- 探索IBD中形肥胖症的新兴问题,包括其病原和治疗.
主要方法:
- 审查关于IBDs中的肉症的当前文献.
- 讨论诊断工具,如超声波和握力测试.
- 探索"肠-肌肉轴"假设和导致炎症和营养不良等因素.
主要成果:
- 麻症对IBD患者产生负面影响,增加手术风险,减少治疗反应,并降低生活质量.
- 抵抗运动,营养支持 (特别是蛋白质) 和抗TNF疗法在治疗IBD患者的肉症方面表现有前途.
结论:
- 麻症是IBD的重要并发症,需要有针对性的诊断和治疗方法.
- 进一步研究IBDs中的sarcopenic肥胖症对于理解和管理这种复杂的疾病至关重要.
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