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Updated: Jun 22, 2025

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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微卫星不稳定的癌症基因组的一个子集,易于短插入而不是删除,与高抗癌免疫力有关

Sunmin Kim1,2,3, Dong-Jin Han1,2,3, Seo-Young Lee1,2,3

  • 1Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Genes
|June 27, 2024
PubMed
概括

DNA不匹配修复缺陷在癌症中产生了不同的基因组足迹. 研究人员确定了两种亚型,插入主导和删除主导,具有独特的遗传和免疫特征,这表明其临床含义不同.

关键词:
修复DNA的修复DNA的修复抗癌免疫力 抗癌免疫力印度的印地尔.微卫星的不稳定性突变的签名 突变的签名

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