猪的生物机械建模 猪的生物机械建模
Aadarsh Mishra1, Robin O Cleveland1
1Department of Engineering Science, University of Oxford, Wellington Square, Oxford OX1 2JD, UK.
Bioengineering (Basel, Switzerland)
|June 27, 2024
概括
这项研究使用振荡式剪切测试来表征猪脏粘弹性. 半分数凯尔文-沃伊格特模型准确地描述了组织.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 器官生物力学 器官生物力学
背景情况:
- 了解组织生物力学对于医疗器械设计和手术规划至关重要.
- 脏组织表现出复杂的粘弹性特性,影响其机械行为.
- 准确的粘性弹性建模对于预测负载下组织反应至关重要.
研究的目的:
- 研究来自不同解剖区域的猪脏组织的粘弹性特性.
- 评估不同粘弹性模型 (标准线性固体,半分数凯尔文-沃伊格特,麦克斯韦-维赫特) 适用于描述组织行为的适用性.
- 为了确定最适合频率和时间域数据的模型.
主要方法:
- 在猪脏组织样本上进行了振荡剪切测试.
- 测量包括储存模块和损失模块作为频率和应变幅度的函数.
- 数据与标准线性固体 (SLS),半分数凯尔文-沃伊格特 (SFKV) 和麦克斯韦-维赫特模型相匹配.
主要成果:
- 半分数凯尔文-沃伊格特 (SFKV) 模型表现出非常适合频率和时间域数据 (相关系数=0.99).
- 标准线性固体 (SLS) 模型在捕捉损失模量 (相关系数 = 0.53) 的频率依赖方面存在局限性.
- 五个参数的麦克斯韦尔-维赫特模型比SLS模型更适合,但SFKV模型 (相关系数=0.85) 的表现优于它.
结论:
- 半分数凯尔文-沃伊格特模型对于描述猪脏组织的粘弹性行为是非常有效的.
- 这些发现为生物机械建模和涉及脏组织的应用提供了宝贵的数据.
- 准确的粘弹性建模对于在各种生理和病理条件下了解脏组织机制至关重要.
相关概念视频
Kidney Structure
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
External Anatomy of the Kidney
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Internal Anatomy of the Kidney
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...


