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穿孔器与非穿孔器基于片的 Vulvoperineal 重建-一个系统性审查和元分析
Séverin Wendelspiess1,2, Loraine Kouba2, Julia Stoffel1
1Department of Medicine, University of Basel, 4056 Basel, Switzerland.
Cancers
|June 27, 2024
概括
在 vulvoperineal 重建中穿孔片的短期并发症率与非穿孔片的短期并发症率相似,并趋向于更少的并发症. 需要进一步的研究来评估长期结果和患者的生活质量 (QoL).
科学领域:
- 手术瘤学手术瘤学
- 重建性手术是一种重建性手术.
- 妇科瘤学 妇科瘤学
背景情况:
- 晚期 vulvoperineal 癌症需要多学科治疗,以确保瘤安全和生活质量 (QoL).
- 这一地区的重建手术具有很高的并发症率 (大约1. 只有30%).
- 穿孔器门旨在通过保存解剖结构来最大限度地减少功能缺陷和供体部位并发症.
研究的目的:
- 在女性 vulvoperineal 重建中比较穿孔器和非穿孔器板之间的手术结果.
- 评估接受这些重建技术的患者的并发症频率.
主要方法:
- 1980年以后发表的英语语言研究的系统审查.
- 包括随机对照试验,队列研究和病例系列.
- 随机效应元分析以汇集并发症频率数据.
主要成果:
- 包括1840名患者在内的49项研究符合纳入标准.
- 在穿孔器 (n=276) 和非穿孔器板 (n=1564) 之间,整体的短期外科并发症率是可比的.
- 穿孔片的并发症较少的趋势被观察到;患者的生活质量数据有限.
结论:
- 与非穿孔板相比,使用穿孔板进行 Vulvoperineal 重建显示出有希望的结果.
- 对长期结果的进一步调查和系统的患者生活质量评估是有必要的.
- 穿孔器片可能在 vulvoperineal 重建中提供好处,但需要更多的数据.
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