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Updated: May 5, 2026

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

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双向双样本孟德尔随机化研究免疫球蛋白GN-糖化和衰老相关的分泌表现型

Haotian Wang1, Di Liu2, Xiaoni Meng1

  • 1Beijing Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing 100069, China.

International journal of molecular sciences
|June 27, 2024
PubMed
概括

这项研究使用了门德尔的随机化来研究免疫球蛋白G (IgG) N-甘氨酸与衰老相关分泌表型 (SASP) 之间的因果关系. 研究结果表明双向因果关系,可能揭示出老化过程中的新调节机制.

关键词:
通过IgG N-糖化.门德尔的随机化年龄化的衰老.与衰老相关的分泌表现型 (SASP)

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相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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