相关实验视频

Updated: May 12, 2026

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
10:40

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Published on: December 21, 2019

26.0K

对COVID-19主要蛋白酶抑制剂的理性方法:一个分层的生物化学信息学分析

Ruan S Bastos1,2, Christiane P O de Aguiar1, Jorddy N Cruz2

  • 1Graduate Program in Medicinal Chemistry and Molecular Modeling, Federal University of Pará, Belém 66075-110, PA, Brazil.

International journal of molecular sciences
|June 27, 2024
PubMed
概括

选择的化合物显示出作为SARS-CoV-2 Mpro抑制剂的承诺. 计算分析证实了稳定的相互作用和有利的结合,表明了新的COVID-19治疗的潜力.

关键词:
这就是SARS-CoV-2病毒.结合性亲和力是一种结合性亲和力.药物开发是药物的发展.分子对接的分子对接.分子动力学分子动力学

更多相关视频

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions08:31

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

5.0K
Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors10:29

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

537

相关概念视频

Inhibitors of Viral Protein Synthesis01:30

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...