声音唤起的神经活动在正常听力耳:频率的影响和刺激耳边耳朵
Shahin Safazadeh1,2,3, Marc Thioux1,2,3, Remco J Renken2,3
1Department of Otorhinolaryngology/Head and Neck Surgery, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.
Brain sciences
|June 27, 2024
概括
没有听力损失的耳会显示听力皮层的过度活跃,特别是在低频率. 这种幻象声音感知可能涉及大脑反应和空间定向的改变.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 神经成像是一种神经成像.
背景情况:
- 耳是一种幻听感知,通常与听力损失引起的大脑可塑性有关.
- 耳可以发生在没有临床听力损失的情况下,使其潜在机制不清楚.
- 之前对正常听力 tinnitus 的大脑活动的研究已经产生了不一致的结果.
研究的目的:
- 通过使用 monaural 刺激来研究 tinnitus 和正常听力的人群中声音唤起的大脑活动的差异.
- 在没有听力损失的情况下探索耳的神经相关性.
主要方法:
- 功能磁共振成像 (fMRI) 用于测量声音引起的反应.
- 研究对象包括有 tinnitus 和没有 tinnitus 的参与者,所有人的听力图都是正常的.
- 呈现了单耳纯音调刺激 (3538000 Hz).
主要成果:
- 主要成分分析 (PCA) 证实了听觉皮层的正常音色组织.
- 通用线性模型 (GLM) 分析显示,侧侧听力皮层区域的过度活动,特别是低频率.
- 在副海马体中观察到刺激侧和耳之间的相互作用.
结论:
- 听力皮层的过度活跃,特别是低频率,即使没有听力损失,也可能与耳有关.
- 这种过度活跃可能与听过度有关.
- 副海马活动表明,耳,大脑处理和空间定向之间存在联系.
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