在长期COVID-19感染中神经认知和神经精神病学后续
Marta Almeria1, Juan Carlos Cejudo2, Joan Deus3,4
1Department of Neurology, Hospital Universitari MútuaTerrassa, 08221 Terrassa, Spain.
Brain sciences
|June 27, 2024
概括
长期COVID认知问题与疾病严重程度无关,但与疲劳和焦虑等持续症状有关,影响整体认知. 注意力,处理速度和执行功能测试最好地检测出这些变化.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
背景情况:
- 长期COVID是SARS-CoV-2感染后的疾病,可能会出现持续的症状,影响各种器官系统.
- 认知功能障碍,通常被称为"大脑雾",是COVID-19经常报告的连续症.
- 了解认知特征及其相关性对于患者管理和康复至关重要.
研究的目的:
- 研究从COVID-19中恢复过来的个体的认知表现.
- 探索认知状态与临床症状,情绪状态和疾病严重程度之间的关联.
- 确定敏感的神经心理测试,以检测COVID-19后患者的认知变化.
主要方法:
- 一项涉及108名参与者 (20至60岁) 的横截面队列研究评估了离院6个月后的情况.
- 参与者根据住院状态和治疗强度 (非住院,住院,氧气治疗,ICU) 进行分类.
- 进行了神经认知评估,排除了具有先前认知或严重神经精神疾病的个体.
主要成果:
- 35.18%的参与者报告了主观认知投诉 (SCC).
- 根据COVID-19疾病严重程度,没有观察到显著的认知差异.
- 持续的疲劳,焦虑和抑郁与整体认知功能较差有关,特别是在注意力,处理速度和执行功能方面.
结论:
- 长期COVID的认知障碍与感染的初始严重程度没有直接相关.
- 主观认知投诉与更高水平的焦虑和抑郁有关,而不是客观认知缺陷.
- 持续的症状,如疲劳和情绪障碍显著影响认知功能,突出需要全面的评估和管理策略.
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