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内分泌石化耳朵:耳部化/骨化中的相关内分泌条件 (以样本为中心的分析)

Ana Valea^1,2, Claudiu Nistor^3,4, Mihai-Lucian Ciobica^4,5

¹Department of Endocrinology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Diagnostics (Basel, Switzerland)

|June 27, 2024

概括

石化耳朵 (PE),耳软骨的化或骨化,其原因尚不清楚. 这份审查强调了与PE相关的内分泌条件,提出了一个新的术语和评估工作流程.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
内分泌学在内分泌学.
病理学病理学病理学

背景情况:

石化耳朵 (PE),以耳软骨的化或骨化为特征,病原性特征不明.
对于PE的内分泌评估缺乏标准化的协议,需要进一步调查相关的荷尔蒙和代谢因素.

研究的目的:

审查关于石化耳朵的最新数据,重点关注其与内分泌和非内分泌条件的关联.
分析PE的表现,诊断工具,荷尔蒙评估,活检发现,结果和病原特征.
提出术语"内分泌石化耳朵"和评估其激素背景的工作流程.

主要方法:

从2000年1月到2024年3月,PubMed的综合文献审查.
包括75名PE受试者从案例报告,系列和回顾性成像研究中.
重新分析和重新分类内分泌PE (EPE) 病例,包括新案例介绍.

主要成果:

最终的EPE队列 (N=50) 显示上腺功能不充分 (36%) 是最常见的内分泌疾病,其次是下腺 (22%) 和甲状腺功能低下 (18%).
在上腺功能衰竭的患者中,39%患有亚迪逊病;初级甲状腺功能低下症占甲状腺功能低下症病例的72%.
在18%的EPE病例中诊断出内分泌自身免疫成分.

结论:

石化耳朵与各种内分泌疾病有关,特别是上腺功能不充分,下垂体,甲状腺功能低下.
提出的术语"内分泌石化耳朵"和标准化的工作流程可以帮助评估PE的荷尔蒙背景.
需要进一步的研究来阐明PE与内分泌功能障碍相关的致病机制.

关键词:

上腺上腺上腺活组织活检耳部软骨的化耳部软骨的化皮质醇是一种皮质醇.内分泌系统内分泌系统内分泌激素激素激素激素激素激素激素激素骨化骨化骨化一个石化耳朵.手术手术手术手术手术手术手术甲状腺是什么?甲状腺是什么?

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