癌症患者的思维风格,情绪反应,创伤后生长 (PTG) 和生物标志物之间的关系
Mariana Sierra-Murguía1, Martha L Guevara-Sanginés2, Gabriela Navarro-Contreras3
1Cancer Center Tec100, Ignacio Zaragoza 263 H16, Col. Centro, Querétaro 76000, QE, Mexico.
概括
癌症患者的思维方式显著影响情绪反应. 化与痛苦有关,而认知参与促进创伤后生长 (PTG),这也与炎症生物标志物相关.
科学领域:
- 心理神经免疫学 心理神经免疫学
- 在瘤学瘤学.
- 临床心理学 临床心理学
背景情况:
- 癌症诊断与严重的情绪困扰有关,包括焦虑,抑郁和创伤后生长 (PTG).
- 思考方式,如反省,认知回避和认知参与,被认为是癌症情绪反应的调解者.
- 了解这些关系对于开发有针对性的心理干预至关重要.
研究的目的:
- 研究癌症患者的思维方式和情绪反应之间的关联.
- 探索情绪反应和炎症免疫生物标志物之间的关系.
- 确定认知过程如何影响癌症患者的心理健康和生理标志物.
主要方法:
- 115名癌症患者在治疗前被评估,使用医院焦虑和抑郁量表 (HADS),应急温度计和创伤后生长库存 (PTGI).
- 分析了患者的血液生物识别,以获得免疫生物标志物.
- 进行了相关性分析,以检查思维方式,情绪反应和生物标志物之间的关系.
主要成果:
- 化显示与焦虑,抑郁和痛苦有显著的相关性.
- 认知参与与PTG正相关 (0.393),而认知回避与PTG负相关 (-0.240).
- 在思维方式,情绪反应 (PTG) 和炎症生物标志物 (如中性粒细胞,淋巴细胞和中性粒细胞与淋巴细胞比率 (NLR) 之间发现了特定的相关性.
结论:
- 思想风格是癌症诊断对情绪反应的重要决定因素.
- 化与负面的情绪状态有关,而认知参与与像PTG这样的积极结果有关.
- 癌症患者的创伤后生长与炎症和免疫学标志物有关,这表明心理神经免疫学联系.
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