抗COVID-19疫苗接种改变月经周期,剂量积累增强了效果
Hospital Español de Pachuca Research Group1, Roque D Licona-Meníndez2, Alberto N Peón2
1Hospital Español de Pachuca, Pachuca 42088, Mexico.
Medicina (Kaunas, Lithuania)
|June 27, 2024
概括
重复接种抗COVID-19疫苗可能会增加女性月经周期变化的可能性. 需要进一步的研究来了解剂量依赖的风险,并开发更安全的疫苗配方.
科学领域:
- 免疫学 免疫学 免疫学
- 生殖健康 生殖健康
- 疫苗学 疫苗学 疫苗学
背景情况:
- 新出现的证据表明,抗COVID-19疫苗接种和月经周期变化之间存在联系.
- 由于免疫力下降,建议进行补充疫苗接种,但它们对不良事件的影响尚不清楚.
研究的目的:
- 为了调查抗COVID-19疫苗接种后的月经周期变化的发生率和数量.
- 评估反复接种COVID-19疫苗对月经周期的剂量依赖性影响.
主要方法:
- 进行了一项针对受疫苗接种的生育年龄妇女的队列研究.
- 通过每月一次的电话通话管理的标准化问卷追踪了疫苗接种后六个月的月经周期变化.
- 使用统计分析,包括赔率比率和二次函数来评估数据.
主要成果:
- 抗COVID-19疫苗接种与月经周期变化的可能性增加有关 (OR 1.52,p < 0.0001).
- 观察到剂量依赖的趋势,与更多的疫苗剂量相关的变化增加 (R2 = 0.91).
- 这些发现在不同的疫苗品牌中是一致的,并且独立于荷尔蒙避孕或多囊性卵巢综合征.
结论:
- 虽然接种疫苗对公共健康至关重要,但反复接种抗COVID-19疫苗可能会增加与月经周期有关的不良事件的风险.
- 该研究强调了开发新型疫苗配方以提供更长时间的免疫力的重要性,以减轻剂量积累风险.
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