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全免疫-炎症值与与冠状动脉血管学结合的对比诱导病之间的关联

Suleyman Akkaya¹, Umit Cakmak²

¹Department of Cardiology, Health Sciences University, Gazi Yasargil Research and Training Hospital, 21100 Diyarbakir, Turkey.

Medicina (Kaunas, Lithuania)

|June 27, 2024

概括

全免疫炎症值 (PIV) 可以预测冠状动脉血管造影后的对比诱导性病 (CIN) 风险. 在接受心血管手术的患者中,较高的PIV水平和较高的年龄与增加的CIN风险有关.

科学领域:

心脏病学心脏病学
腎臟病學 (nephrology) 是一種醫學專業.
炎症生物标志物炎症生物标志物

背景情况:

对比诱导性病 (CIN) 是心血管手术后的一种严重并发症.
炎症在CIN的发展中起着关键作用.
基于周围血液的指数提供了作为可访问的CIN生物标志物的潜力.

研究的目的:

调查泛免疫炎症值 (PIV) 和CIN风险之间的关联.
评估PIV作为冠状动脉血管学后CIN的预测生物标志物.

主要方法:

分析了1343名接受冠状动脉血管造影 (CAG) 的患者队列.
全免疫-炎症值 (PIV) 计算为 (中性细胞数 × 血小板数 × 单细胞数) / 淋巴细胞数.
多变量回归分析确定了CIN的预测因素.

主要成果:

在15%的患者中发生了对比诱导性病 (CIN).
较高的PIV水平 (OR: 1.016) 和较高的年龄 (OR: 1.015) 与增加的CIN风险显著相关.
抗血小板剂的使用与CIN风险降低相关 (OR:0.670).

结论:

升高的PIV水平和晚年是CIN在接受CAG的患者中显著的风险因素.
PIV可以作为预测CIN风险的最小侵入性生物标志物.
需要进一步的前性研究来证实PIV的预测效用.

关键词:

形成对比的诱导性脏病冠状动脉动脉图 (Coronary Angiography) 是一种冠状动脉动脉图.这是一种炎症炎症炎症炎症.全免疫性炎症的价值.

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