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自我报告的睡眠时间是预测智利老年人肉症的有用工具:来自ALEXANDROS长度研究的证据
Myriam Gutiérrez1,2,3, Carlos Márquez1,2,4, Lydia Lera1,5
1Aging, Age and Quality of Life Nucleus, Public Nutrition Unit, Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago 7830490, Chile.
Journal of personalized medicine
|June 27, 2024
概括
睡眠障碍是老年智利人沙科佩尼亚的一个独立风险因素. 识别睡眠问题可以帮助预防肉症,这是一种老年人肌肉损失的疾病.
科学领域:
- 老年学是一门学科.
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 与年龄相关的睡眠障碍和肉症有共同的生物学途径.
- 关于拉丁美洲人群,特别是智利人群中这种关联的前性数据有限.
研究的目的:
- 调查社区居住的智利老年人中睡眠障碍和肉症之间的纵向关联.
- 为了确定睡眠特征作为萨科佩尼亚发展的潜在风险因素.
主要方法:
- 一项队列研究跟踪了来自ALEXANDROS队列的318名年龄≥60岁的智利成年人.
- 收集的数据包括社会人口统计学,慢性疾病,生活方式,睡眠模式,人体测量,手握强度和肌肉性能.
- 调整后的考克斯回归模型被用来分析睡眠障碍和肉眼之间在8.24年的随访期内的关联.
主要成果:
- 萨科佩尼亚的基线患病率为24.10%,自我报告的睡眠问题为23.3%,女性患病率更高.
- 睡眠障碍 (HR=2.08) 和长时间睡眠 (HR=2.42) 显着与缩症的风险增加有关.
- 麻症的发病率为每100人年2.2例.
结论:
- 睡眠障碍是智利老年人中 Sarcopenia 发展的一个独立风险因素.
- 自我报告的睡眠问题可以有助于早期识别患有肉症风险的个人.
- 针对睡眠障碍提供了一种潜在的战略,用于在老年人群中成本有效的预防肉类症.
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