使用小珠进行前列腺动脉栓塞 (PAE),用于治疗良性前列腺增生症 (BPH)
Genti Xhepa1,2, Lucilla Violetta Sciacqua3, Andrea Vanzulli3,4
1Istituto di Imaging della Svizzera Italiana (IIMSI), Ente Ospedaliero Cantonale (EOC), 6900 Lugano, Switzerland.
Journal of personalized medicine
|June 27, 2024
概括
前列腺动脉栓塞 (PAE) 为良性前列腺增生症 (BPH) 提供了一种安全的,最少侵入性的治疗方法. 这项研究发现PAE有效,56%的患者在手术后成功切除了尿导管.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 干预性放射学 干预性放射学
背景情况:
- 良性前列腺增生 (BPH) 是一种常见的疾病,在老年男性中引起下泌尿道症状 (LUTS).
- 由于安全性和有效性,BPH的最小侵入性治疗越来越受青.
- 前列腺动脉栓塞 (PAE) 是一种新兴的微创手术选择,其结果与前列腺过尿道切除 (TURP) 相似.
研究的目的:
- 评估前列腺动脉栓塞 (PAE) 对良性前列腺增生 (BPH) 的临床结果.
- 评估PAE在前列腺体积减小和LUTS缓解方面的有效性.
- 为了确定尿路导管切除后PAE程序的可行性.
主要方法:
- 在2015年10月至2022年11月期间,对24名连续接受PAE治疗的患者进行了回顾性评估.
- PAE涉及选择性透前列腺动脉和使用不同大小的颗粒 (40-120μm,100μm,100-300μm,250μm) 的栓塞.
- 主要终点是在第一次术后泌尿器科诊所取出尿管时进行的.
主要成果:
- 在所有患者中都取得了技术上的成功,定义为选择性导管和受控的栓塞.
- 没有报告任何主要的术前并发症.
- 56%的患者在手术后成功地切除了尿导管.
结论:
- 前列腺动脉栓塞 (PAE) 是对良性前列腺增生症 (BPH) 的技术成功和安全的微创治疗方法.
- PAE显示出显著的LUTS缓解和改善生活质量的潜力,以高水平的导管独立为证.
- 需要进一步的研究来确定PAE程序的最佳颗粒大小.
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