相关实验视频

Updated: Jun 22, 2025

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

11.9K

使用机器学习增强的对接和分子动力学,探索与膜结合的粉样分子结合的纤维分解和抗氧化分子

Luthary Segura1, Natalia Santos2, Rafael Flores3

  • 1Neuroscience Department, Trinity University, San Antonio, TX 78212, USA.

Molecules (Basel, Switzerland)
|June 27, 2024
PubMed
概括

新的阿尔茨海默氏症研究表明,向纤维的分子也可能与早期神经毒性膜结合的含寡合物 (mTCOs) 结合,提供新的治疗途径.

关键词:
粉样蛋白的小分子.化学信息学 化学信息学药物设计 药物设计药物与蛋白质的相互作用机器学习是机器学习.分子药物对接的对接神经退行性疾病是一种神经退行性疾病.蛋白质折叠 蛋白质的折叠

更多相关视频

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

9.2K
Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis13:31

Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis

Published on: February 12, 2015

8.8K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.5K