基于高分辨率质谱和化学分析的地理Erigeron breviscapus可追溯性研究
Jiao Zhang1,2, Heng Tian1,3,4, Tao Lin1
1Institute of Quality Standards and Testing Technology, Yunnan Academy of Agricultural Sciences, Agricultural Product Quality Supervision and Inspection Center, Ministry of Agriculture, Kunming 650223, China.
Molecules (Basel, Switzerland)
|June 27, 2024
概括
使用质谱法确定了Erigeron breviscapus的地理起源. 发现了特定的化学标记,可能揭示了这种重要的药用草本的合成途径.
科学领域:
- 植物化学 植物化学
- 化学测量 化学测量 化学测量
- 药理学是指药理学,即药理学是指药理学.
背景情况:
- 埃里根 (Honghe Dengzhanhua) 是一种有价值的药用植物.
- 确定药用植物的地理来源对于质量控制和认证至关重要.
- 目前用于追踪植物起源的方法可能缺乏精度.
研究的目的:
- 开发和应用一种方法来识别和追踪Erigeron breviscapus的地理来源.
- 区分来自云南和贵州各省各地区的样本.
- 发现潜在的生物标志物来确定地理原产地.
主要方法:
- 高分辨率质谱法 (HRMS) 用于化学分析.
- 化学测量方法,包括主要成分分析 (PCA) 和部分最小平方差分分析 (PLS-DA),用于数据分析.
- 代表性样本从洪河州和云南和贵州省的其他地点收集.
主要成果:
- 在不同地理来源之间观察到不同的化学特征.
- PCA和PLS-DA图表有效地区分了样本组.
- 在洪河州和贵州的样本中共发现了46种特征性化合物,其中37种化合物与云南其他地区不同.
- 两种潜在的生物标志物,8-amino-7-oxononanoic acid和8-hydroxyquinoline,被确定具有相同的分子组成.
结论:
- 开发的方法成功地确定并追踪了Erigeron breviscapus的地理来源.
- 已识别的生物标志物可以作为植物起源的指标.
- 进一步的研究可以阐明这些生物标志物的合成途径.
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