未来的,随机的,双盲并行组营养研究,以评估日常摄入新鲜酸奶与巴氏消毒酸奶对健康成年人免疫系统的影响
Fernando Rivero-Pino1,2, Mar Casquete3, Maria José Castro4
1Department of Medical Biochemistry, Molecular Biology, and Immunology, School of Medicine, University of Seville, 41009 Seville, Spain.
Nutrients
|June 27, 2024
概括
新鲜酸奶可以增强特定的免疫反应,如IgM和T细胞,而新鲜和巴氏化酸奶可以提高先天免疫力. 新鲜酸奶中的活细菌是强化特异性免疫效应的关键.
科学领域:
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
- 微生物学 微生物学
背景情况:
- 饮食摄入量显著影响免疫系统调节.
- 在临床和健康人群中,营养在管理免疫媒介慢性疾病方面发挥着重要作用.
- 酸奶是一种常见的食产品,正在研究其免疫调节潜力.
研究的目的:
- 为了比较新鲜酸奶与巴氏化酸奶的免疫系统调节效应.
- 调查日常饮用酸奶对健康成年人免疫反应的影响.
主要方法:
- 这是一项为期8周的单中心,前性,随机,双盲,并行组研究.
- 健康的成年人每天三次摄入125克新鲜或消毒酸奶.
- 进行了全面的体外免疫系统活性测试.
主要成果:
- 新鲜酸奶的摄入增加了全身IgM,IFN-马合成和天真的CD4+T细胞.
- 这两种酸奶都增强了颗粒细胞的细胞活性,促炎性细胞因子分泌 (IL-6,IL-1β,IL-8) 和CD16表达.
- 新鲜酸奶中的活细菌与增强的特定免疫反应有关.
结论:
- 酸奶的消费,无论细菌活力如何,都会影响天生的免疫系统.
- 新鲜酸奶中的活细菌对于增强特定免疫反应至关重要.
- 饮食酸奶可以调节先天和特异性免疫功能.
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