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Updated: Jun 23, 2026

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肠道淋巴吸收的体外预测模型:探索额外的增强剂和抑制剂

Malaz Yousef1,2, Conor O'Croinin1, Tyson S Le1

  • 1Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada.

Pharmaceutics
|June 27, 2024
PubMed
概括

这项研究引入了一种体外模型来预测通过肠道淋巴体吸收药物的情况. 由于中链脂肪酸,子油增强了吸收,显示了配方开发的模型实用性.

关键词:
基微粒子是一种基微粒子.增强剂是一种增强剂.在体外 (in vitro) 的情况下.抑制剂 抑制剂 抑制剂淋巴细胞吸收的情况

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Methods for Studying Drug Absorption: In vitro01:16

Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...