甲状腺切除术后的阳性性低甲状腺功能障碍的发展:一项回顾性队列研究
Amal A Alomari1,2, Raneen N Abu Shanab1,2, Randa A Bajunaid1,2
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Endocrinology, diabetes & metabolism
|June 27, 2024
概括
阳性甲状腺缺血症影响37.9%的甲状腺切除术后患者,广泛的淋巴结解剖增加了风险. 在11.66%的病例中,永久性副副甲状腺功能障碍发生,这突显了需要警监测和管理的必要性.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 甲状腺手术 甲状腺手术
背景情况:
- 阳性甲状腺功能低下症是甲状腺切除术后的常见并发症,导致低血症.
- 沙特阿拉伯的发病率差异很大,从0.07%到65.30%.
- 症状从轻度到重度,可能危及生命.
研究的目的:
- 为了确定甲状腺手术后的阳性性低甲状腺症的发生率和预测因素.
- 为了研究甲状腺切除术后这种情况的自然过程.
主要方法:
- 追溯队列研究分析了2017-2022年的数据.
- 从电子医疗保健系统中提取患者的人口统计数据,手术细节和生物化学资料.
- 包括343名接受甲状腺切除术的患者.
主要成果:
- 总共有130名患者 (37.9%) 患上了副副甲状腺功能障碍,主要是在手术后24小时内.
- 广泛的联合淋巴结解剖与缺甲状腺症 (p=0.0004) 有关.
- 在40名患者 (11.66%) 诊断出永久性偏偏甲状腺症.
结论:
- 该研究发现,在甲状腺切除术后,有较高的阳性性甲状腺功能低下症发病率和显著的永久性甲状腺功能低下症发病率.
- 需要进一步的研究来阐明风险因素和优化管理策略.
- 强调警的术后监测和及时的替代疗法的重要性.
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