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Updated: Apr 11, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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使用Hi-C指导的多聚合物模型来破译3D基因组组织

Chen Shi1, Lei Liu1, Changbong Hyeon2

  • 1Key Laboratory of Optical Field Manipulation of Zhejiang Province, Department of Physics, Zhejiang Sci-Tech University, Hangzhou, China.

Biophysical journal
|June 27, 2024
PubMed
概括

一个新的聚合物模型从染色体构造捕获数据中生成多个规模的基因组结构. 这种模型揭示了染色体大小对核定位的影响,并澄清了隔间分布,提供了对3D基因组组织的见解.

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