从软固体中穿孔实验的力量分解和性估计.
Pranav Shrestha1, Curtis Geffner1, Matthew Jaffey1
1Department of Mechanical Engineering, The University of British Columbia, 2054-6250 Applied Science Lane, Vancouver, British Columbia, V6T 1Z4, Canada. pranav.shrestha@alumni.ubc.ca.
Soft matter
|June 27, 2024
概括
针插入机制尚未完全理解. 这项研究表明,材料性随着插入速度的增加而增加,这表明在高速时组织变硬.
科学领域:
- 生物力学 生物力学
- 材料科学 材料科学 材料科学
- 医疗设备工程 医疗设备工程
背景情况:
- 针和微针插入对于药物输送和生物传感等医疗应用至关重要.
- 针插入的机械行为,特别是在高速时,仍然不太了解.
- 分析针插入力的现有方法可能无法完全捕捉复杂的物质相互作用.
研究的目的:
- 研究在不同速度 (0.1毫米/秒到2.3米/秒) 插入中空洞针的机械过程.
- 开发一种先进的方法,将插入力分解为不同的组件 (偏移,摩擦/扩散,切割).
- 为了确定材料断裂性质的拉伸率依赖性,例如性.
主要方法:
- 在透明的样品上使用双插入技术.
- 采用成像,图像分析和力测量来量化插入力.
- 开发了一种新的方法来分离力组件:偏向 (Fd),摩擦/扩散 (Ff + Fs) 和切割 (Ft).
主要成果:
- 发现材料性 (Γ) 随着针插入速度的增加而增加.
- 计算的性值与类似材料的现有文献报告的性值一致.
- 其他机械参数,包括临界力 (Fc) 和工作 (Wc),也表明了应变率的依赖.
结论:
- 针插入力和由此产生的材料特性取决于速度.
- 高速插入导致材料性增加,并表明由于累积的应变能量而导致组织硬.
- 开发的力分解方法提供了更准确的了解针-组织相互作用.
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