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一个处理大规模巧合错误的处理 De Novo 抗体由自下而上的蛋白质组的测序

Douwe Schulte1, Joost Snijder1

  • 1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands.

Journal of proteome research
|June 27, 2024
PubMed
概括

拼接软件 (v1.5) 从数据重建抗体序列,通过解决质量错误和模两可的残留物来提高准确性. 新功能增强了 de novo 序测序的兼容性和容错性.

关键词:
调整对齐的情况抗体是对抗体的重要组成部分.在 de novo 测序中使用 de novo 测序.这是一种异酸盐 (isobaric).质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量一个序列组装组件.

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