在塞拉利昂进行集群采样,重新评估九个特有地区的杆菌病
Ibrahim Kargbo-Labour1, Victoria Redwood-Sawyerr2, Abdulai Conteh1
1National Neglected Tropical Disease Control Program, Ministry of Health and Sanitation, Freetown, Sierra Leone.
Frontiers in public health
|June 27, 2024
概括
在塞拉利昂,经过十年的大规模药物管理后,istosomiasis 的患病率显著下降. 然而,针对性干预仍然需要在高发病率的族长中消除这种疾病.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 热带医学 热带医学
背景情况:
- 在塞拉利昂的九个地区,杆菌病具有高度/中度的特有性.
- 大规模药物管理 (MDA) 与praziquantel开始于2009年.
- 2016年和2022年进行了影响评估,以改进治疗策略.
研究的目的:
- 评估MDA对塞拉利昂istosomiasis患病率的影响.
- 提供细粒度数据,以完善首领级别的治疗策略.
- 为了评估学校儿童当前的杆菌病负担.
主要方法:
- 系统地选择9个地区的每个地区的20个村庄.
- 随机选择每所学校24名学龄儿童 (5-14岁) 进行便和尿液样本采集.
- 使用Kato-Katz检查便样本以检测Schistosoma mansoni,通过Hemastix和过检查尿液样本以检测Schistosoma haematobium.
主要成果:
- 总体上,S. mansoni的流行率为16.3%,S. haematobium的流行率为2.0%.
- 严重感染的发生率为S. mansoni的1.5%,S. haematobium的0.02%.
- 在65个族长中,体病的发病率为<10%,在47个族长中为10-49.9%,在13个族长中为≥50%.
结论:
- 塞拉利昂在减少杆菌病的流行率方面取得了重大进展.
- 高患病率热点仍然存在,需要进一步调查和有针对性的干预措施.
- 可能需要考虑在热点首领区进行社区范围的治疗.
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