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相关概念视频

Phylogeny01:23

Phylogeny

43.8K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
43.8K
Phylogenetic Trees03:21

Phylogenetic Trees

45.3K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
45.3K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

4.8K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
4.8K
Synteny and Evolution02:31

Synteny and Evolution

3.2K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.2K
Pedigree Analysis01:35

Pedigree Analysis

84.2K
Overview
84.2K

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相关实验视频

Updated: Jun 22, 2025

A Practical Guide to Phylogenetics for Nonexperts
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A Practical Guide to Phylogenetics for Nonexperts

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PhyloJS:通过一个JavaScript实用程序库将遗传学和Web开发联系起来.

Leo A Featherstone1, Wytamma Wirth1

  • 1Peter Doherty Institute for Infection and Immunity University of Melbourne Melbourne Victoria Australia.

Ecology and evolution
|June 27, 2024
PubMed
概括
此摘要是机器生成的。

PhyloJS是一个新的JavaScript库,用于解析,写作和操纵家族遗传树. 这个工具可以高效地处理大型数据集,从而实现基于Web的先进的遗传学应用程序.

关键词:
这是JavaScript的JavaScript.人类遗传学 是一个学科.网站开发 网站开发

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An Integrated Approach for Microprotein Identification and Sequence Analysis
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An Integrated Approach for Microprotein Identification and Sequence Analysis

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A Web Tool for Generating High Quality Machine-readable Biological Pathways
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A Web Tool for Generating High Quality Machine-readable Biological Pathways

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相关实验视频

Last Updated: Jun 22, 2025

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An Integrated Approach for Microprotein Identification and Sequence Analysis
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An Integrated Approach for Microprotein Identification and Sequence Analysis

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A Web Tool for Generating High Quality Machine-readable Biological Pathways
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A Web Tool for Generating High Quality Machine-readable Biological Pathways

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科学领域:

  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学
  • 网站开发 网站开发

背景情况:

  • 用于家族遗传树操纵的JavaScript库通常将可视化与有限的操纵功能和文档捆绑在一起.
  • 越来越大的遗传学数据集需要专门的工具用于基于Web的应用程序.

研究的目的:

  • 介绍PhyloJS,一个轻量级,零依赖的TypeScript和JavaScript库,用于家族遗传树操作.
  • 提供一种解决方案来解析,写作和操纵家族遗传树,并增强互操作性.

主要方法:

  • 开发了PhyloJS作为一个TypeScript和JavaScript库.
  • 确保零依赖,方便整合.
  • 为高效处理大型遗传树木进行了优化.

主要成果:

  • PhyloJS允许修改和提取从家族遗传树上的数据.
  • 图书馆可以处理高达10^6个尖端的树.
  • 便于与其他遗传学和数据可视化库集成.

结论:

  • PhyloJS解决了对基于Web的族系遗传学的强大,可互操作的库的需求.
  • 它对大型数据集的效率支持下一代应用程序的开发.
  • 通过npm可以轻松访问该库,并提供全面的文档.