超导管大动脉置换后的亚临床小册子血栓和抗凝策略:系统性审查
Singam Shashank1, Lalitha Devi Balireddi2, Pugazhendi Inban3
1Shadan Institute of Medical Sciences Hyderabad India.
Health science reports
|June 27, 2024
概括
亚临床传单血栓瘤 (SLT) 发生在15%的跨导管大动脉置换 (TAVR) 患者中. 双重抗血小板治疗可能会加速SLT,损害门功能.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 干预心脏病学 干预心脏病学
背景情况:
- 亚临床传单血栓症 (SLT) 影响了15%的患者在通过透气管进行大动脉置换后 (TAVR).
- TAVR涉及将故障的大动脉置换成机械式的大动脉,不同于外科大动脉置换 (SAVR).
- 在TAVR后无症状SLT的最佳治疗方法,包括口服抗凝剂 (OAC),仍未确定.
研究的目的:
- 系统地审查经过过导管大动脉置换 (TAVR) 后的亚临床传单血栓症 (SLT) 的文献.
- 分析SLT在TAVR患者中的患病率,特征和影响.
- 评估当前抗血栓治疗方案对SLT进展的影响.
主要方法:
- 使用PubMed,Medline和Cochrane评论对已发表的研究进行系统审查.
- 包含基于预先定义的标准的原始论文和评论.
- 关键词包括"透导管置换"和"亚临床传单血栓症".
主要成果:
- 在TAVR后,SLT的发病率高于外科上门置换 (SAVR) 之后.
- 双重抗血小板治疗 (DAPT) 可能会加速SLT的进展.
- 加速的SLT可以导致传单的移动性受损,压力梯度增加.
结论:
- 在TAVR后的常规双重抗血小板治疗可能会加速亚临床传单血栓形成.
- 这种加速可能会导致传单的移动性受到限制,压力梯度升高.
- 需要进一步的研究来确定最佳的抗血栓策略,以治疗TAVR后的SLT.
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