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Updated: Jun 9, 2026

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress
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Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress

Published on: August 31, 2015

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基于元分析的应变设计,以缓解生物制造中重要的氧化应力

P V Phaneuf1, S H Kim1, K Rychel2

  • 1Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, Building 220. Kongens Lyngby 2800, Denmark.

ACS synthetic biology
|June 27, 2024
PubMed
概括

这项研究使用了元分析来发现突变,改善微生物菌株对活性氧物种 (ROS) 应激的抵抗力. 在oxyR,毛皮,iscR和ygfZ中发现的突变增强了耐受性,并减少了生物制造的细胞应激反应.

关键词:
在ALE突变中,ALE突变发生.这是一个SOS响应SOS响应.酸性压力是一种酸性压力.在iModulons中使用.基准分析驱动的应变设计.有活性氧物种的反应性氧物种.

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