[药物过量使用头痛患者的睡眠障碍]
I A Kniazeva1,2, D V Gilev3, E R Lebedeva1,2
1Ural State Medical University, Yekaterinburg, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|June 27, 2024
概括
药物过度使用头痛 (MOH) 的患者比没有MOH的患者更容易出现睡眠障碍,包括慢性失眠和不安腿综合征. 早期诊断和治疗这些睡眠问题对于管理MOH进展至关重要.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 头痛 疾病 头痛 疾病
背景情况:
- 药物过度使用头痛 (MOH) 是频繁头痛治疗的常见并发症.
- 睡眠障碍在头痛患者中经常被报告,但它们与MOH的特定关联需要进一步调查.
研究的目的:
- 为了比较MOH患者的睡眠障碍投诉和诊断睡眠障碍的发生率,与没有MOH的初级头痛患者相比.
主要方法:
- 一项前性病例控制研究,涉及171名MOH患者和173名非MOH初级头痛患者.
- 神经学检查,专业面试和标准化尺度,包括国际睡眠障碍分类 (第三版). ),失眠严重程度指数,爱普沃思睡眠度量表和NoSAS.
- 基于国际睡眠障碍分类 (2014年第3版) 的睡眠障碍诊断.
主要成果:
- 患有MOH的患者报告睡眠丧失 (51.5%),经常醒来 (43.3%) 和不安腿综合征 (37.4%) 的比率显著更高.
- MOH患者的慢性失眠发生率较高 (60.2%对47.4%,p=0.02) 和不安腿综合征 (37.4%对22.0%,p=0.002).
- 困难入睡,白天嗜睡和打的发病率在各组之间是相似的;高睡眠症和阻塞性睡眠呼吸暂停综合征没有显著差异.
结论:
- 与非MOH头痛患者相比,MOH患者的睡眠障碍,特别是慢性失眠和不安腿综合征的患病率明显高.
- 这些发现强调了睡眠障碍在MOH病理生理学中的关键作用.
- 及时诊断和管理睡眠障碍对于预防MOH和睡眠障碍的恶化至关重要.
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